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. 2022 Nov 30;17(11):e0278259. doi: 10.1371/journal.pone.0278259

Fig 3. Comparison of healthy adolescent and adult microbial and metabolomic profiles.

Fig 3

(A) Principal coordinate analysis (PCoA) showing bacterial ordination by age group at baseline. (B) Bacterial Shannon diversity boxplots, and (C) Taxonomy composition barplots, comparing age groups at baseline, day 17 and day 30. (D) Heatmap, and (E) Boxplots, of differentially abundant ASVs between age groups over time points. (F) Principal component analysis (PCA) showing metabolomic ordination by age group at baseline. (G) Heatmap, and (H) Boxplots, of differentially abundant metabolites between age groups over time points. Boxplots are indicative of median, interquartile range (IQR) (boxes) and 1.5x IQR (whiskers). *, p < 0.05; n.s., not significant.