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. 2022 Nov 30;17(11):e0278259. doi: 10.1371/journal.pone.0278259

Fig 5. Comparison of antibiotic-treated adolescent and adult microbial and metabolomic profiles.

Fig 5

(A) Principal coordinate analysis (PCoA) showing bacterial ordination by age group and treatment at day 30. (B) Bacterial Shannon diversity boxplots, and (C) Taxonomy composition barplots, comparing treatment and age groups at day 30. (D) Heatmap of differentially abundant ASVs between treatment groups at day 30. (E) Principal component analysis (PCA) showing metabolomic ordination by age group and treatment at day 30. (F) Heatmap of differentially abundant metabolites between treatment groups at day 30. (G) Boxplots of differentially abundant metabolites between age groups at day 30. Boxplots are indicative of median, interquartile range (IQR) (boxes) and 1.5x IQR (whiskers). n.s., not significant.