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TABLE 1.

G. lamblia infections in immunodeficient mice

Expt Mice Day 7
Day 14
Day 28
Infecteda Intensityb Infected Intensity Infected Intensity
1 C57BL/6J 3/3 7.1 ± 4.4 1/3 0.3 ± 0.6 0/3  NDg
B6 Igh-6 3/3 22.1 ± 6.3cd 1/3 0.3 ± 0.6d 0/3 ND
B6 SCID 3/3 164.2 ± 62.1c 3/3 197.1 ± 100.3c 3/3e 150.8 ± 15.8
B6 TCRβ 3/3 45.0 ± 8.2cd 3/3 51.7 ± 12.1cd 3/3e 53.8 ± 17.7d
2 C57BL/6J 3/3 13.3 ± 11.1 2/3 1.3 ± 1.2 1/3 0.3 ± 0.6
B6 SCID 3/3 79.2 ± 37.4c 3/3 185.0 ± 73.7c 3/3 140.0 ± 47.7c
B6 TCRβ 3/3 185.0 ± 50.7cd 3/3 91.7 ± 36.2cdf 3/3 50.0 ± 10.0cdf
a

The number of mice with detectable parasites in the gut/total number of mice analyzed on the day indicated postinfection. 

b

The average ± standard deviation of the number of parasites/mouse × 104

c

P < 0.01 versus the value for C57BL/6J mice. 

d

P < 0.01 versus the value for B6 SCID mice. 

e

P < 0.08 versus the value for C57BL/6J mice. 

f

P < 0.01 versus the value on day 7. 

g

ND, none detected.