Skip to main content
. 2022 Nov 29;6(2):e202201437. doi: 10.26508/lsa.202201437

Figure 2. V. cholerae and V. anguillarum share the T6SS Aux1 A-type effector.

Figure 2.

Left: Maximum-likelihood tree built on 30 Vibrio genomes collapsed by species. Bootstrap support values are indicated. Scale represents substitutions per amino acid site. Pie charts showing the distribution of V. cholerae Aux1 A- and C-type effectors in each species. The novel V. anguillarum/V. ordalii T6SS cluster Acc Aux1 is included in the pie charts as it uniformly encodes the V. cholerae Aux1 A-type effector. Individual strain effector sets are shown in the expanded phylogenetic trees for each species in the supplement (Figs S3 and S4). Right: Diagrams of representative Aux1 clusters in the V. cholerae clade, the V. fluvialis/V. furnissii clade, and the V. anguillarum clade as well as the Acc Aux1 cluster found in the V. anguillarum clade. Putative gene transfer event of the A-type effector-immunity module between the V. anguillarum clade and the V. cholerae clade is indicated by a dashed arrow. Pandemic V. cholerae strains are shown in bold.