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. 2021 Jun 18;293:78–89. doi: 10.1016/j.jad.2021.06.021

Table 3.

Total and subgroup meta-analysis of pooled prevalence d (%, 95%CI) of depression, anxiety, sleep disorders, and posttraumatic stress symptoms among children during the COVID-19 pandemic based on the included studies a

Type of analysis Groups N of studies Prevalence (%, 95% CI) P value Heterogeneity
I2 (%) χ2 P Tau-squared
Depression Total 12 28.6 (17.2, 40.1) <0.001 99.9 8025.91 <0.001 0.0405
Anxiety Total 13 25.5 (16.0, 35.1) <0.001 99.9 10690.46 <0.001 0.0307
Sleep disorders b Total 2 44.2 (20.7, 67.7) <0.001 94.8 19.22 <0.001 0.0273
Posttraumatic stress symptoms c Total 2 48.0 (-25.4, 121.4) 0.200 100 3364.24 <0.001 0.2804
Depression Children (≤12 years) 3 11.8 (1.3, 22.3) 0.028 98.9 183.35 <0.001 0.0085
Adolescents (13-18 years) 8 34.4 (18.2, 50.7) <0.001 99.9 7695.86 <0.001 0.0548
Anxiety Children 6 15.7 (9.0, 22.3) <0.001 98.7 389.71 <0.001 0.0066
Adolescents 11 29.1 (17.1, 41.1) <0.001 99.9 10269.07 <0.001 0.0407
Depression Male 4 28.9 (14.1, 43.7) <0.001 99.6 670.02 <0.001 0.0228
Female 5 33.9 (24.6, 43.1) <0.001 99.2 506.21 <0.001 0.0110
Anxiety Male 7 22.3 (14.2, 30.4) <0.001 99.1 650.31 <0.001 0.0118
Female 7 27.4 (20.3, 34.6) <0.001 98.6 431.08 <0.001 0.0091
a

All the studies included in meta-analysis were from China and among general children and adolescents, so no subgroup meta-analysis was conducted based on country and pre-existing conditions of children and adolescents.

b

Only two articles were found on sleep disorders, one was conducted among children and both boys and girls, the age and gender of participants in the other study were not reported, so no subgroup analysis was conducted based on age and gender.

c

Only two articles were found on posttraumatic stress symptoms, both studies did not report the age of participants and the gender-stratified prevalence, so no subgroup meta-analysis was conducted based on age and gender.

d

Prevalence was calculated based on the random-effect models.