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. Author manuscript; available in PMC: 2022 Nov 30.
Published in final edited form as: Nat Med. 2022 Oct 3;28(10):2027–2037. doi: 10.1038/s41591-022-02028-2

Table 1 |.

Pooled effect sizes from meta-analyses comparing mental health symptoms before versus during the first year of the COVID-19 pandemic in the general population

Pooled studies n (sample size) Pooled effect size (95% CI)
Mental health problems (mixed outcomes)
Robinson et al.13 61 (55,015) 0.11 (0.04–0.17)
 Mar–Apr 2020 0.10 (0.03–0.19)
 May–Jul 2020 0.07 (−0.02–0.16)
Patel et al.15 11 (49,993)
 Apr–Jun 2020 0.15 (0.06–0.23)
 Jul–Oct 2020 0.18 (0.09–0.27)
 Nov–Mar 2021 0.21 (0.10–0.32)
Prati et al.14 20 (72,004) 0.17 (0.07–0.26)
Depression symptoms
 Robinson et al.13 58 0.22 (0.14–0.30)
 Prati et al.14 9 0.15 (0.01–0.30)
Anxiety symptoms
 Robinson et al.13 52 0.13 (0.02–0.23)
 Prati et al.14 10 0.17 (0.07–0.27)
Psychotic symptoms
 Robinson et al.13 5 −0.21 (−0.38 to −0.05)
Well-being
 Robinson et al.13 7 0.07 (−0.12–0.26)
 Prati et al.14 7 −0.12 (−0.33–0.09)
Loneliness
 Ernst et al.16 24 (45,734) 0.27 (0.14–0.40)