Table 2.
Baseline characteristics among three groups.
| Variable | T 1 | T 2 | T 3 | P value |
|---|---|---|---|---|
| N | 290 | 291 | 291 | |
| Male (n, %) | 207 (71.4) | 170 (58.4) | 177 (60.8) | 0.003 |
| Age (years) | 63.0 ± 9.1 | 65.0 ± 9.3 | 65.8 ± 9.3 | 0.001 |
| BMI (kg/m2) | 25.1 ± 3.1 | 24.9 ± 3.2 | 25.2 ± 3.1 | 0.698 |
| Prior stroke (n, %) | 64 (22.1) | 56 (19.2) | 66 (22.7) | 0.558 |
| Hypertension (n, %) | 203 (70.0) | 209 (71.8) | 215 (73.9) | 0.581 |
| Diabetes (n, %) | 75 (25.9) | 96 (33.0) | 94 (32.3) | 0.120 |
| Smoking (n, %) | 86 (29.7) | 84 (28.9) | 74 (25.4) | 0.483 |
| Anemia (n, %) | 27 (9.3) | 39 (13.4) | 62 (21.3) | <0.001 |
| CKD (n, %) | 9 (3.1) | 4 (1.4) | 7 (2.4) | 0.375 |
| NSTEMI (n, %) | 47 (16.2) | 35 (12.0) | 73 (25.1) | <0.001 |
| CHF (n, %) | 15 (5.2) | 26 (8.9) | 43 (14.8) | <0.001 |
| SBP (mmHg) | 137.1 ± 19.9 | 137.0 ± 19.3 | 135.9 ± 18.6 | 0.713 |
| DBP (mmHg) | 78.0 ± 12.4 | 76.7 ± 12.0 | 76.8 ± 12.6 | 0.366 |
| Leukocyte (109/L) | 6.2 (5.2, 7.3) | 6.5 (5.6, 7.9) | 6.8 (5.8, 8.1) | <0.001 |
| Hemoglobin (g/L) | 143.1 ± 13.6 | 138.0 ± 15.4 | 135.6 ± 15.5 | <0.001 |
| Platelet (109/L) | 198 (164, 232) | 196 (163, 237) | 199 (170, 243) | 0.224 |
| Fasting blood glucose (mmol/L) | 5.8 (5.2, 6.9) | 5.8 (5.2, 7.2) | 5.9 (5.2, 7.9) | 0.564 |
| SCr (μmol/L) | 74 (63, 86) | 74 (64, 86) | 78 (67, 91) | 0.006 |
| eGFR (mL/min/1.73 m2) | 91.0 (77.8, 102.3) | 86.2 (72.3, 98.3) | 81.3 (68.5, 95.9) | <0.001 |
| Uric acid (μmol/L) | 350 (295, 406) | 335 (288, 412) | 364 (297, 417) | 0.101 |
| Triglyceride (mmol/L) | 1.5 (1.0, 2.2) | 1.4 (1.0, 2.0) | 1.5 (1.1, 2.1) | 0.471 |
| TC (mmol/L) | 4.5 (3.7, 5.1) | 4.4 (3.7, 5.2) | 4.5 (3.8, 5.2) | 0.585 |
| HDL-C (mmol/L) | 1.1 (1.0, 1.3) | 1.1 (0.9, 1.3) | 1.1 (0.9, 1.2) | 0.020 |
| LDL-C (mmol/L) | 2.7 (2.1, 3.3) | 2.6 (2.0, 3.3) | 2.7 (2.1, 3.4) | 0.422 |
| PT (s) | 11.4 ± 1.1 | 11.5 ± 2.5 | 11.5 ± 1.3 | 0.825 |
| APTT (s) | 30.7 ± 4.1 | 31.1 ± 6.7 | 31.0 ± 3.7 | 0.622 |
| D-dimer (μg/L) | 71 (43, 119) | 95 (55, 153) | 113 (66, 181) | <0.001 |
| Fibrinogen (g/L) | 3.1 ± 0.4 | 3.8 ± 0.3 | 4.4 ± 0.4 | <0.001 |
| Albumin (g/L) | 41.9 ± 3.2 | 40.6 ± 3.2 | 38.4 ± 3.1 | <0.001 |
| FAR (%) | 7.5 ± 0.9 | 9.3 ± 0.4 | 11.4 ± 0.9 | <0.001 |
| Mehran score | 1 (1, 4) | 4 (1, 5) | 4 (1, 6) | <0.001 |
| HbA1c (%) | 6.0 (5.5,6.5) | 6.1 (5.7, 6.9) | 6.1 (5.6, 7.1) | 0.008 |
| LVEF (%) | 68 (63, 72) | 67 (63, 72) | 67 (60, 73) | 0.617 |
| Procedural characteristics | ||||
| Left main disease (n, %) | 16 (5.5) | 19 (6.5) | 26 (8.9) | 0.252 |
| Three-vessel disease (n, %) | 99 (34.1) | 108 (37.1) | 130 (44.7) | 0.027 |
| Number of stents | 1.5 ± 0.6 | 1.5 ± 0.7 | 1.5 ± 0.6 | 0.992 |
| Contrast volume (mL) | 100 (100, 100) | 100 (100, 100) | 100 (100, 100) | 0.938 |
| Hydration (n, %) | 255 (87.9) | 237 (81.4) | 222 (76.3) | 0.001 |
| Medication use (n, %) | ||||
| Aspirin | 285 (98.3) | 284 (97.6) | 288 (99.0) | 0.433 |
| Clopidogrel/ticagrelor | 289 (99.7) | 291 (100) | 290 (99.7) | 0.443 |
| ACEI/ARB | 155 (53.4) | 157 (54.0) | 173 (59.5) | 0.271 |
| β-Blockers | 215 (74.1) | 227 (78.0) | 241 (82.8) | 0.039 |
| Statin | 288 (99.3) | 290 (99.7) | 291 (100) | 0.248 |
| Diuretics | 20 (6.9) | 31 (10.7) | 45 (15.5) | 0.004 |
| PC-AKI (n, %) | 18 (6.2) | 25 (8.6) | 71 (24.4) | <0.001 |
PC-AKI: postcontrast acute kidney injury; BMI: body mass index; CKD: chronic kidney disease; NSTEMI: non-ST elevation myocardial infarction; CHF: congestive heart failure; SBP: systolic blood pressure; DBP: diastolic blood pressure; SCr: serum creatinine; eGFR: estimated glomerular filtration rate; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; PT: prothrombin time; APTT: activated partial thromboplastin time; FAR: fibrinogen-to-albumin ratio; HbA1c: hemoglobin A1c; LVEF: left ventricular ejection fraction; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker.