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. 2022 Oct 26;612(7938):106–115. doi: 10.1038/s41586-022-05249-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — a,b) HSCN from 2 individual cells from the OV2295 cell line. c) Total copy number heat maps and HSCN heat map for 1084 cells. Each row is an individual cell. Rows are ordered according to a UMAP + HDBSCAN clustering, with clusters annotated on the left hand side. d) Distribution of VAFs as a function of haplotype-specific state. e,f,g) VAFs in clones where the dominant allele switches between A and B. Each point is the VAF of a mutation, with lines connecting the same mutation in different clones.