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. 2022 Nov 17;9:921829. doi: 10.3389/fcvm.2022.921829

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Copyright © 2022 Zhang, Zuo, Li, Wang, Huang, Xu, Jin, Lu and Dai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The densities of autophagosomes and autolysosomes in zebrafish cardiomyocytes are quantified when treated with statins. (A) Quantification of the density of autophagosomes in 3-dpf zebrafish heart of Tg(myl7:EGFP-LC3) line when treated with indicated statins. (B) Quantification of the densities of autophagosomes in 3-dpf zebrafish heart of Tg(myl7:mRFP-EGFP-LC3) line when treated with indicated statins. (C) Quantification of the densities of autolysosomes in 3-dpf zebrafish heart of Tg(myl7:mRFP-EGFP-LC3) line when treated with indicated statins. The data are shown as mean ± s.e.m for each group. n = 13 in the control group, n = 19 in the atorvastatin group, n = 4 in the fluvastatin group, n = 11 in pitavastatin, n = 24 in the pravastatin group, and n = 13 in the rosuvastatin group. *p < 0.05, **p < 0.01, ***p < 0.001.