Table 2.
Activity of disorazol F2 (1) against human cancer cell lines (IC50, nM).
| Compounds | HepG2 | HCT116 | A549 |
|---|---|---|---|
| F2 (1) | 0.25 ± 0.01 | 3.11 ± 0.10 | 2.74 ± 0.56 |
| Vincristine | 6.62 ± 0.48 | 50.05 ± 3.68 | 44.28 ± 4.55 |
| Doxorubicin | 830 ± 119 | 793 ± 90 | 919 ± 35 |
IC50 values are calculated from three independent biological replicates.