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. 2022 Nov 30;8:166. doi: 10.1038/s41531-022-00436-2

Table 1.

Vantaa dataset.

spSa spTh DMV LC SN AMY TOX # cases # OB pos. % OB pos.
EARLY AMYGDALA-PREDOMINANT CASES
x 2 2 100
x x 1 1 100
x x 1 1 100
x x x 1 1 100
TOTAL 5 5 100
EARLY BRAINSTEM/PNS-PREDOMINANT CASES
x 4 0 0
x x 6 0 0
x x 1 0 0
x x 1 0 0
x x x x 2 1 50
x x x 1 1 100
x x x x x 1 0 0
TOTAL 16 2 13
EARLY OTHER CASES
x 2 1 50
x x 4 4 100
TOTAL 6 5 83

The Vantaa dataset had 27 early-stage cases with minimal Lewy-type pathology ordered into amygdala-predominant, brainstem/PNS-predominant cases, and other cases categories. Each row in the table represents a distinct pattern of pathology shared by a number of cases (# cases). An “x” signifies the presence of Lewy-type pathology in individual anatomical structures. The three right-most columns list the total number of cases of each type, the number of OB-positive cases, and the percentage of OB-positive cases.

spSa sacral spinal cord, spTh thoracic spinal cord, DMV dorsal motor nucleus of vagus, LC locus coeruleus, SN substantia nigra, AMY amygdala, TOX transentorhinal cortex, OB olfactory bulb.