Table 1.
spSa | spTh | DMV | LC | SN | AMY | TOX | # cases | # OB pos. | % OB pos. |
---|---|---|---|---|---|---|---|---|---|
EARLY AMYGDALA-PREDOMINANT CASES | |||||||||
x | 2 | 2 | 100 | ||||||
x | x | 1 | 1 | 100 | |||||
x | x | 1 | 1 | 100 | |||||
x | x | x | 1 | 1 | 100 | ||||
TOTAL | 5 | 5 | 100 | ||||||
EARLY BRAINSTEM/PNS-PREDOMINANT CASES | |||||||||
x | 4 | 0 | 0 | ||||||
x | x | 6 | 0 | 0 | |||||
x | x | 1 | 0 | 0 | |||||
x | x | 1 | 0 | 0 | |||||
x | x | x | x | 2 | 1 | 50 | |||
x | x | x | 1 | 1 | 100 | ||||
x | x | x | x | x | 1 | 0 | 0 | ||
TOTAL | 16 | 2 | 13 | ||||||
EARLY OTHER CASES | |||||||||
x | 2 | 1 | 50 | ||||||
x | x | 4 | 4 | 100 | |||||
TOTAL | 6 | 5 | 83 |
The Vantaa dataset had 27 early-stage cases with minimal Lewy-type pathology ordered into amygdala-predominant, brainstem/PNS-predominant cases, and other cases categories. Each row in the table represents a distinct pattern of pathology shared by a number of cases (# cases). An “x” signifies the presence of Lewy-type pathology in individual anatomical structures. The three right-most columns list the total number of cases of each type, the number of OB-positive cases, and the percentage of OB-positive cases.
spSa sacral spinal cord, spTh thoracic spinal cord, DMV dorsal motor nucleus of vagus, LC locus coeruleus, SN substantia nigra, AMY amygdala, TOX transentorhinal cortex, OB olfactory bulb.