Table 2.
Clinical resource use and outcome components
| Complete sample (n = 21,810) | PROPPR (n = 881) | PROMMTT (n = 2,510) | Traumabase (n = 1,765) | Experts (n = 2,738) | Most cited (n = 3,527) | |
|---|---|---|---|---|---|---|
| Transfusion in resuscitation room | ||||||
| RBC | 0 [0; 0] | 3 [2; 4] | 2 [1; 4] | 2 [0; 4] | 0 [0; 2] | 0 [0; 2] |
| FFP | 0 [0; 0] | 0 [0; 3] | 0 [0; 2] | 0 [0; 3] | 0 [0; 0] | 0 [0; 0] |
| Platelets | 0 [0; 0] | 0 [0; 0] | 0 [0; 0] | 0 [0; 0] | 0 [0; 0] | 0 [0; 0] |
| Transfusion at 24 h | ||||||
| RBC | 0 [0; 1] | 8 [4; 14] | 6 [4; 12] | 8 [6; 14] | 4 [0; 9] | 3 [0; 8] |
| FFP | 0 [0; 0] | 6 [2; 10] | 4 [2; 8] | 6 [3; 10] | 2 [0; 6] | 0 [0; 5] |
| Platelets | 0 [0; 0] | 1 [0; 2] | 0 [0; 1] | 1 [0; 2] | 0 [0; 1] | 0 [0; 1] |
| Massive transfusion | 895 (4.6) | 323 (40.6) | 744 (32.5) | 700 (43.0) | 594 (23.9) | 622 (19.5) |
| Tranexamic acid | 4602 (26.3) | 706 (83.4) | 1,633 (73.5) | 1,176 (76.2) | 1,525 (63.0) | 1,770 (57.2) |
| Fibrinogen concentrate | 1005 (5.7) | 392 (46.5) | 816 (36.8) | 644 (41.7) | 635 (26.3) | 697 (22.6) |
| Surgery/IR | ||||||
| Immediate | 849 (4.8) | 243 (28.5) | 413 (18.4) | 351 (22.3) | 292 (11.9) | 371 (11.9) |
| within 24 h | 10,128 (46.4) | 589 (66.9) | 1,754 (69.9) | 1,323 (75.0) | 1,733 (63.2) | 1,924 (54.6) |
| Mortality | ||||||
| 24 h | 721 (3.6) | 150 (18.2) | 356 (15.0) | 254 (15.1) | 286 (11.1) | 499 (15.1) |
| In-hospital | 2,182 (11.0) | 305 (37.1) | 818 (34.5) | 604 (35.8) | 711 (27.7) | 1,190 (36.0) |
| Organ failure | ||||||
| ARDS | 1,252 (12.6) | 142 (26.1) | 383 (23.6) | 314 (26.0) | 443 (24.8) | 518 (24.0) |
| RRT | 302 (2.8) | 71 (11.5) | 170 (9.4) | 153 (11.5) | 175 (8.9) | 182 (7.4) |
| LOS | ||||||
| In hospital | 8 [3; 19] | 14 [2; 38] | 16 [3; 40] | 17 [2; 42] | 16 [4; 38] | 10 [2; 32] |
| In ICU | 3 [2; 7] | 6 [2; 18.75] | 6 [2; 17] | 6 [2; 18] | 6 [2; 18] | 5 [2; 15] |
Variables are reported as median [IQR1, IQR3] or n (%); Massive transfusion is defined as more than 10 RBC in the first 24 h;
For each of the five definitions of THS, the number of patients selected using a given definition is presented in the first line of the table. As example, using the PROPPR definition would have conducted to identify among the 21,810 of the complete sample 881 as being in THS
RBC red blood cell, FFP fresh frozen plasma, IR interventional radiology, ARDS acute respiratory distress syndrome, RRT renal replacement therapy, LOS length of stay, ICU intensive care unit