Box 1.

THS definitions

Most frequently cited definition

SBP ≤ 70 mmHg

OR

SBP 71–90 mmHg if heart rate ≥ 108/bpm

Expert definition

Shock Index ≥ 1.0 during prehospital care or in resuscitation room

AND

Based excess at hospital arrival ≤ -5.0 mmol/L

PROPPR study

> 1 RBC during prehospital stage or in resuscitation room

AND

ABC score [5] ≥ 2:

Penetrating mechanism (gunshot, stabbing)

Positive focused assessment sonography for trauma (hemoperitoneum)

SBP at hospital arrival ≤ 90 mmHg

Heart rate at hospital arrival ≥ 120 bpm

PROMMTT study

At least 1 RBC within 6 h

The Traumabase definition

At least 4 RBC within the first 6 h

Supplementary material 2 present the detailed components used in the database to categorize patients in groups

RBC red blood cell, SBP systolic blood pressure