Table 1.
Score points | |||||
---|---|---|---|---|---|
Parameter | 0 | 1 | 2 | 3 | Score |
Primary site | Gonadal | Extragonadal | – | Mediastinal | |
Response to first-line treatment | CR/PRm- | PRm + /SD | PD | – | |
PFI (months) | < 3 | ≤ 3 | – | – | |
AFP at relapse | Normal | ≤ 1.000 | > 1.000 | – | |
HCG at relapse[Unit] | ≤ 1.000 | > 1.000 | – | – | |
LBB | No | yes | – | – |
Final scoring based on histology and risk group scores
AFP alpha-1-feto protein, CR complete remission, HCG ß-subunit of human chorionic gonadotropin, IPFSG International Prognostic Factor Study Group, LBB presence of liver, brain or bone metastasis, PRm + marker-positive partial remission, PRm- marker-negative partial remission, PFI progression-free interval, SD stable disease