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. 2022 Feb 28;40(12):2853–2861. doi: 10.1007/s00345-022-03959-8

Table 1.

IPFSG Prognostic Score for patients with relapsing non-seminomas and seminomas

Score points
Parameter 0 1 2 3 Score
Primary site Gonadal Extragonadal Mediastinal
Response to first-line treatment CR/PRm- PRm + /SD PD
PFI (months)  < 3  ≤ 3
AFP at relapse Normal  ≤ 1.000  > 1.000
HCG at relapse[Unit]  ≤ 1.000  > 1.000
LBB No yes

Final scoring based on histology and risk group scores

AFP alpha-1-feto protein, CR complete remission, HCG ß-subunit of human chorionic gonadotropin, IPFSG International Prognostic Factor Study Group, LBB presence of liver, brain or bone metastasis, PRm + marker-positive partial remission, PRm- marker-negative partial remission, PFI progression-free interval, SD stable disease