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. 2022 Nov 17;9:995749. doi: 10.3389/fmed.2022.995749

TABLE 3.

The results of the univariate Cox proportional hazards model.

Exposure Statistics HR (95% CI) P-value
Gender
Male 6502 (54.680%) Ref
Female 5389 (45.320%) 1.055 (0.966, 1.152) 0.23380
Age (years) 43.293 ± 14.953 1.006 (1.003, 1.009) 0.00006
ALP (U/L) 71.831 ± 22.208 1.009 (1.008, 1.010) < 0.00001
GGT (U/L) 27.023 ± 18.032 1.017 (1.016, 1.019) < 0.00001
HDL-c (mmol/L) 1.451 ± 0.357 0.285 (0.249, 0.327) < 0.00001
GGT/HDL-c ratio 20.044 ± 14.312 1.030 (1.028, 1.032) < 0.00001
ALT (U/L) 19.550 ± 15.365 1.007 (1.006, 1.008) < 0.00001
AST (U/L) 22.730 ± 8.830 1.008 (1.006, 1.011) < 0.00001
ALB (g/L) 44.543 ± 2.773 0.994 (0.979, 1.010) 0.46073
GLB (g/L) 29.284 ± 3.987 1.019 (1.008, 1.030) 0.00060
TBIL (umol/L) 12.264 ± 5.053 0.984 (0.976, 0.993) 0.00051
DBIL (umol/L) 2.206 ± 1.196 0.730 (0.702, 0.758) < 0.00001
BUN (umol/L) 4.585 ± 1.413 0.876 (0.847, 0.907) < 0.00001
Scr (umol/L) 83.431 ± 25.654 1.003 (1.001, 1.004) < 0.00001
UA (umol/L) 291.675 ± 88.578 1.002 (1.002, 1.003) < 0.00001
FPG (mmol/L) 5.205 ± 0.827 1.219 (1.186, 1.253) < 0.00001
TC (mmol/L) 4.601 ± 0.731 1.307 (1.232, 1.386) < 0.00001
TG (mmol/L) 1.346 ± 0.835 1.414 (1.384, 1.445) < 0.00001
LDL-c (mmol/L) 2.272 ± 0.470 1.799 (1.628, 1.988) < 0.00001
BMI (kg/m2) 21.590 ± 2.039 1.679 (1.629, 1.730) < 0.00001
SBP (mmHg) 122.216 ± 16.916 1.014 (1.012, 1.016) < 0.00001
DBP (mmHg) 73.664 ± 10.337 1.033 (1.029, 1.037) < 0.00001

Values are n (%) or mean ± SD.

BMI, Body mass index; SBP, Systolic blood pressure; ALP, Alkaline phosphatase; DBP, Diastolic blood pressure; GGT, γ-glutamyl transpeptidase; TC, Total cholesterol; ALT, Alanine aminotransferase; Scr, Serum creatinine; LDL-C, Low-density lipid cholesterol; AST, Aspartate aminotransferase; ALB, albumin; GLB, globulin; TG, Triglyceride; UA, uric acid; HDL-C, High-density lipoprotein cholesterol; BUN, Serum urea nitrogen; FPG, Fasting plasma glucose; DBIL, Direct bilirubin; TBIL, Total bilirubin; GGT/HDL-c ratio, Gamma -glutamyl transpeptidase to high-density lipoprotein cholesterol ratio; HR, Hazard ratios; CI, confidence interval; Ref, reference.