Table 3.

Identification of multi-gene families using Paralog Explorer.

Query Ligand	Known Paralogs	Identified via Paralog Explorer (DIOPT Score)	% of known identified
dpp	gbb, scw, daw, mav, myo, Actβ	gbb (4), scw (4), daw (3), mav (3), myo (3), Actβ (2)	100
wg	wnt2, wnt4, wnt5, wnt6, wntD, wnt10	wnt2 (3), wnt4 (4), wnt5 (3), wnt6 (4), wntD (2), wnt10 (3)	100
upd	upd2, upd3	upd2 (2), upd3 (1)	100
Pvf1	Pvf2, Pvf3	Pvf2 (1), Pvf3 (1)	100
spz	NT1 (aka spz2), spz3, spz4, spz5, spz6	NT1 (1), spz3 (1), spz4 (1), spz5 (2), spz6 (1)	100