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. 2022 Nov 25;20:6578–6585. doi: 10.1016/j.csbj.2022.11.045

Table 1.

Overview of m1A modifications in human RNAs.

RNA Position Functions
tRNA 9 Formation of cloverleaf structure; Stabilization of tRNA structure [35]
mt-tRNA 9 Formation of cloverleaf structure; Stabilization of tRNA structure [19], [36]
tRNAPhe 14 Unknown [16]
tRNA 58 Promotion of translation; Stabilization of tRNAiMet[15], [29]
mt-tRNA 58 Unknown [12]
mt-16S rRNA 947 Stabilization of mitochondrial ribosome [22]
28S rRNA 1322 Formation of ribosome 60S subunit [37]
mRNA All segments Promotion of translation [9]
ATP5D mRNA A71 at Exon 1 Suppression of translation elongation [38]
mt-mRNA CDS Prevent the effective translation of modified codons [6]
ND5 mt-mRNA 1374 Unknown [24]
MALAT1 lncRNA 8398 Unknown [24]