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TABLE 3.

Gene usage by fine specificities for each MAb panel

MAb Specificity by FELISA Fusion pIa VH gene
181.1 OAc >>> MCPS 1 7.2–7.9 VH10
1702.10 OAc >> MCPS 2 ND Q52
1922.2 OAc >> MCPS 2 ND Q52
2016.3 OAc >> MCPS 3 8.3–8.6 J558
C2/273.7 OAc >> MCPS B ND J558
C2/655.7 OAc >> MCPS C 5.6–6.7 J558
C2/969.3 OAc >> MCPS E ND J558
CP163.6 OAc >> MCPS 1B 7.1–7.6 J558
177.16 OAc > MCPS 1 6.8–7.2 J558
C2/181.7 OAc > MCPS B 6.7–7.6 J558
1946.13 MCPS >>> OAc 2 6.7–7.2 J558
C2/205.10 MCPS >>> OAc B 6.7–7.0 Q52
3079.6 MCPS > OAc 6 8.2–8.3 Q52
C2/630.10 MCPS > OAc C 6.3–6.7 J558
C2/735.4 MCPS > OAc D 6.7–7.1 VGAM3-8
C2/951.8 MCPS > OAc E 6.7–7.3 J558
CP1050.20 MCPS > OAc 3A 6.9–7.3 J558
C2/35.3 MCPS ≈ OAc A 7.0–7.4 7183
C2/233.2 MCPS ≈ OAc B 6.1–6.4 Q52
C2/256.8 MCPS ≈ OAc B 6.7–7.0 J558
C2/998.3 MCPS ≈ OAc E 6.2–6.5 J558
CP882.2 MCPS ≈ OAc 2B 6.8–7.1 7183
CP875.2 MCPS ≈ OAc 2B 6.9–7.2 J558
CP947.6 MCPS ≈ OAc 2B 7.0–7.5 J558
CP1049.19 MCPS ≈ OAc 3A 6.1–7.2 VGAM3-8
CP1160.12 MCPS ≈ OAc 4B 6.8–7.5 J558
CP1092.23 MCPS ≈ OAc 4B 6.9–7.5 J558
3624.22 MCPS 7 ND 3609
2750.27 MCPS 4 7.6–8.1 3609
78.2 MCPS 1 6.1–6.8 3609
1705.18 MCPS 2 7.9–8.3 J558
1846.13 MCPS 2 8.1–8.3 J558
1863.5 MCPS 2 ND J558
2055.5 MCPS 3 8.4–8.8 J558
3006.18 MCPS 5 7.6–8.1 J558
2010.10 OAc ≥ MCPS >> K92 3 ND X24
C2/706.12 OAc > MCPS >>> K92 D 6.4–7.6 7183
C2/974.1 MCPS ≈ OAc >>> K92 E 6.4–6.9 J558
C2/1076.10 MCPS ≈ OAc >>> K92 E 6.4–6.8 7183
a

pI data for the MCPS MAbs are from reference 51 and are reproduced with the permission of The Journal of Immunology. ND, not determined.