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. 2022 Nov 17;13:1026660. doi: 10.3389/fphar.2022.1026660

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Copyright © 2022 Xiao, Xu, Tan, Zhang, Wang, Wang, Yang, Bai, Song, Shi, Lyu, Zhang and Hou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ZZKZ promoted weight gain, food intake, gastric emptying and intestinal propulsion in FD rats. (A) The study protocol of FD models and treatment. (B) Changes in body weight, and (C) body weight gain in the week after ZZKZ treatment in different groups. N = 6–8; *p < 0.05, **p < 0.01 (D–E) Food intake in different groups, including quick eating (3-h food intake) and total ingestion (24-h food intake). N = 6–8; *p < 0.05 vs. HC; ^# p < 0.05, ^## p < 0.01 vs. FD. (F) Gastric emptying rate for the solid meal, (G) residual rate of phenol red meal, and (H) intestinal propulsion rate in different groups. N = 6–8; *p < 0.05, **p < 0.01 vs. HC; ^# p < 0.05, ^## p < 0.01 vs. FD.