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. 2022 Nov 17;13:1004345. doi: 10.3389/fimmu.2022.1004345

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Copyright © 2022 Deng, Wang, Yang, Zuo, Ji, Bai, Ning, Liu, Wang, Ge, Zhang, Ba and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Peripheral blood single cell atlas of patients with esophageal cancer. (A) Workflow showing the scRNA-seq experimental design and initial data exploration. (B, C) UMAP plot of 18,121 high-quality immune cells to show nine main cell-types based on the expression of known marker genes, colored by cell type and cell origin respectively. (D) The proportion of cells that contributed to each cluster by each sample, colored by cell types. (E) UMAP plot of 18,121 high-quality immune cells to show nine main cell-types based on the cell sources. (F) The proportion of cells that contributed to each cluster.