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. 2022 Nov 17;13:1004345. doi: 10.3389/fimmu.2022.1004345

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Copyright © 2022 Deng, Wang, Yang, Zuo, Ji, Bai, Ning, Liu, Wang, Ge, Zhang, Ba and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single-cell subsets of mononuclear cells in peripheral blood of ESCC. (A)UMAP showing the clustering of monocyte subsets based on the expression of marker genes. Each dot corresponds to one single cell colored according to cell cluster. (B) UMAP showing the merge monocyte cells from ESCC patients. (C) The proportion of cells that contributed to each cluster by each sample. (D) The heat map shows the relative expression levels of differential genes in each subtype of monocytes. (E–G) GO enrichment analysis of monocyte Cluster 1-3.