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. 2022 Nov 17;13:1004345. doi: 10.3389/fimmu.2022.1004345

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Copyright © 2022 Deng, Wang, Yang, Zuo, Ji, Bai, Ning, Liu, Wang, Ge, Zhang, Ba and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of single cell subsets of neutrophils in peripheral blood of ESCC. (A) UMAP showing the clustering of neutrophils subsets based on the expression of marker genes. (B) UMAP showing the merge neutrophils from ESCC patients. (C) The proportion of cells that contributed to each cluster by each sample. (D) The heat map shows the relative expression levels of differential genes in each neutrophil cluster. (E) Neutrophil cluster 1 GO enrichment analysis showed that it was related to MHC class II molecular antigen presentation process. (F–H) GO enrichment analysis of neutrophil Cluster 2-4.