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. 2022 Aug 18;2(6):419–429. doi: 10.1007/s43657-022-00067-w

Table 2.

Differences between health-exam BPs and research-quality BPs of subgroups

Characteristics Mean SBP, mm Hg Mean difference (95% CI) p for interaction Mean DBP, mm Hg Mean difference (95% CI) p for interaction
Health-exam Research-quality Health-exam Research-quality
Overall 139.9 135.7 4.2 (3.9, 4.5) 90.0 86.8 3.3 (3.1, 3.5)
Age, years  < 0.001 0.64
 18–39 136.9 134.9 2.0 (0.9, 3.2) 89.8 86.4 3.5 (2.7, 4.2)
 40–49 139.2 135.2 4.0 (3.5, 4.5) 90.4 87.0 3.4 (3.0, 3.7)
 50–60 140.9 136.2 4.8 (4.3, 5.2) 89.8 86.6 3.2 (2.8, 3.5)
BMI, kg/m2 0.03 0.001
 18.5–23.9 138.9 134.1 4.8 (4.2, 5.5) 88.9 86.1 2.8 (2.4, 3.2)
 24–27.9 139.9 135.6 4.3 (3.8, 4.8) 90.0 86.8 3.2 (2.9, 3.5)
  ≥ 28 140.8 137.3 3.5 (2.9, 4.2) 91.4 87.5 3.9 (3.5, 4.4)
Educational level 0.16 0.10
 ≤ Middle school 139.8 135.6 4.3 (4.0, 4.7) 89.9 86.7 3.2 (3.0, 3.4)
 > Middle school 140.1 136.5 3.7 (2.9, 4.5) 90.9 87.2 3.7 (3.2, 4.2)
Physically activea 0.005 0.002
 Yes 140.1 137.0 3.1 (2.3, 4.0) 90.1 87.8 2.3 (1.7, 2.9)
 No 139.6 135.1 4.5 (4.1, 4.9) 90.0 86.6 3.3 (3.1, 3.6)
Current smoker 0.96 0.06
 Yes 140.4 136.3 4.2 (3.7, 4.7) 90.2 87.3 3.0 (2.7, 3.3)
 No 139.2 135.0 4.2 (3.7, 4.7) 89.8 86.4 3.4 (3.1, 3.7)
Current drinker 0.29  < 0.001
 Yes 140.9 136.8 4.0 (3.6, 4.5) 91.0 87.3 3.7 (3.4, 4.1)
 No 138.9 134.5 4.4 (3.9, 4.9) 89.1 86.2 2.8 (2.5, 3.1)
CVD 0.40 0.83
 Yes 140.7 137.3 3.5 (1.6, 5.3) 90.7 87.5 3.2 (2.0, 4.4)
 No 139.9 135.6 4.2 (3.9, 4.6) 90.0 86.7 3.3 (3.1, 3.5)
DM 0.01 0.04
 Yes 141.6 136.5 5.0 (4.3, 5.8) 89.9 87.1 2.8 (2.4, 3.3)
 No 139.4 135.4 4.0 (3.6, 4.4) 90.1 86.7 3.4 (3.2, 3.7)
Cancer 0.40 0.71
 Yes 138.9 136.8 2.1 (− 3.2, 7.3) 90.2 86.3 3.9 (0.4, 7.4)
 No 139.9 135.7 4.2 (3.9, 4.6) 90.1 86.8 3.3 (3.0, 3.5)
Impaired renal functionb 0.42 0.12
 Yes 140.8 136.1 4.7 (3.5, 5.9) 90.9 87.0 3.9 (3.1, 4.7)
 No 139.8 135.7 4.2 (3.8, 4.5) 90.0 86.8 3.2 (3.0, 3.5)
Time interval of health-exam and research-quality BPs  < 0.001 0.01
 < 10 days 139.7 135.1 4.6 (4.2, 5.0) 90.0 86.5 3.5 (3.2, 3.7)
 10 to < 20 days 140.1 137.1 3.0 (1.6, 4.4) 89.6 87.1 2.5 (1.6, 3.5)
 ≥ 20 days 140.8 138.4 2.3 (1.4, 3.2) 90.7 88.1 2.6 (2.0, 3.2)
Order of health-exam and research-quality BPs 0.46 0.67
 Health-exam before research-quality BPs 139.5 135.4 4.1 (3.6, 4.6) 90.1 86.7 3.3 (3.0, 3.7)
 Health-exam after research-quality BPs 140.1 135.8 4.3 (3.9, 4.8) 90.0 86.8 3.2 (2.9, 3.5)
Use of antihypertensive drugs 0.07  < 0.001
 None 140.4 135.9 4.5 (3.9, 5.0) 90.3 87.1 3.2 (2.9, 3.6)
 Nitrendipine & captoril 139.3 135.3 4.0 (3.4, 4.7) 89.9 86.3 3.6 (3.2, 4.0)
 Nitrendipine & antisterone 138.5 136.1 2.4 (0.8, 4.0) 90.4 86.4 4.1 (3.0, 5.1)
 Hydrochlorothiazide & captoril 139.1 135.7 3.3 (2.0, 4.7) 90.4 86.3 4.0 (3.1, 4.9)
 Hydrochlorothiazide & antisterone 138.5 134.9 3.6 (2.1, 5.1) 90.0 85.7 4.3 (3.3, 5.2)
 Self-administration 140.6 135.8 4.7 (4.0, 5.5) 89.6 87.3 2.3 (1.8, 2.8)
Type of sphygmomanometer  < 0.001  < 0.001
 Mercury vs mercury 138.3 134.1 4.2 (3.6, 4.8) 90.7 86.9 3.8 (3.4, 4.2)
 Electronic vs electronic 142.8 140.6 2.1 (1.0, 3.2) 90.7 87.1 3.6 (2.8, 4.3)
 Mercury vs electronic 138.1 138.9 − 0.9 (− 2.1, 0.4) 92.0 87.7 4.3 (3.5, 5.1)
 Electronic vs mercury 141.0 134.5 6.5 (5.7, 7.4) 87.8 85.6 2.2 (1.7, 2.8)
HMC sites  < 0.001  < 0.001
 One 140.4 139.7 0.7 (− 0.1, 1.5) 91.5 87.1 4.3 (3.8, 4.9)
 Two 139.9 135.8 4.1 (3.1, 5.2) 91.3 88.2 3.1 (2.4, 3.8)
 Three 143.3 134.3 9.1 (5.6, 12.5) 95.8 84.8 11.0 (8.7, 13.2)
 Four 137.9 135.4 2.5 (1.8, 3.2) 87.3 86.6 0.7 (0.2, 1.1)
 Five 145.2 136.5 8.7 (7.2, 10.2) 93.9 87.4 6.5 (5.5, 7.5)
 Six 147.2 142.6 4.6 (0.2, 8.9) 91.7 89.8 1.9 (-1.0, 4.8)
 Seven 144.4 138.0 6.3 (5.2, 7.4) 92.3 90.1 2.0 (1.5, 3.0)
 Eight 148.2 140.8 7.4 (3.1, 11.7) 97.1 91.0 6.1 (3.3, 9.0)
 Nine 135.8 127.5 8.3 (7.5, 9.0) 87.3 81.9 5.4 (4.8, 5.9)
 Ten 143.8 143.3 0.6 (− 1.0, 2.1) 94.7 92.1 2.7 (1.7, 3.7)

BMI body mass index, BP blood pressure, CVD cardiovascular disease, DBP diastolic blood pressure, DM diabetes, HMCs health management centers, SBP systolic blood pressure

aBeing physically active was defined as moderate or vigorous physical activity for ≥ 80 min per week

bImpaired renal function was defined as the presence of albuminuria or estimated glomerular filtration rate < 60 (ml/min/1.73 m2)