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. 2022 Oct 10;37(12):2932–2941. doi: 10.1093/humrep/deac216

Table I.

Fertility patterns among women with a registered reproductive outcome between the age of 15–45 years, according to asthma status.

Total (n = 206693) Reference women without asthma (n = 200248) Women with asthma (n = 6445)
Age at index healthcare visit
 <25 102 648 (51.3%) 3976 (61.7%)
 25–29 45 492 (22.7%) 1274 (19.8%)
 30–34 33 770 (16.9%) 783 (12.1%)
 35–39 14 882 (7.4%) 353 (5.5%)
 40–45 3456 (1.7%) 59 (0.9%)
Approximated age of reproductive start
 <25 38 885 (19.4%) 1456 (22.6%)
 25–29 60 771 (30.3%) 2179 (33.8%)
 30–34 60 187 (30.1%) 1725 (26.8%)
 35–39 30 090 (15.0%) 845 (13.1%)
 40–45 10 315 (5.2%) 240 (3.7%)
Childbirth 164 979 (82.4%) 5329 (82.7%)
Age of delivery
No delivery 35 269 (17.6%) 1116 (17.3%)
 <25 84 949 (42.4%) 3280 (50.9%)
 25–29 40 183 (20.1%) 1113 (17.3%)
 30–34 27 833 (13.9%) 650 (10.1%)
 35–39 10 369 (5.2%) 257 (4.0%)
 40–45 1645 (0.8%) 29 (0.4%)
Year of delivery
 1998–2004 57 415 (28.7%) 749 (11.6%)
 2005–2009 35 652 (17.8%) 1210 (18.8%)
 2010–2014 36 886 (18.4%) 1710 (26.5%)
 2015–2019 35 026 (17.5%) 1660 (25.8%)
Endometriosis 393 (0.2%) 20 (0.3%)
PCOS 1035 (0.5%) 50 (0.8%)
Infertility (diagnosis or treatment)a 16 220 (8.1%) 712 (11.0%)
 With subsequent childbirth 7599 (3.8%) 356 (5.5%)
 Not leading to childbirth 6672 (3.3%) 278 (4.3%)
Infertility diagnosisb 14 792 (7.4%) 642 (10.0%)
 Unspecified 8413 (4.2%) 349 (5.4%)
 Unexplained after examination 2155 (1.1%) 118 (1.8%)
 Myoma 99 (0.0%) 5 (0.1%)
 Ovarian failure 211 (0.1%) 7 (0.1%)
 Anovulation 2176 (1.1%) 88 (1.4%)
 Tubal factor infertility 844 (0.4%) 39 (0.6%)
Medically assisted reproductionc
 Ovulation stimulation 419 (0.2%) 9 (0.1%)
 Intrauterine insemination 596 (0.3%) 39 (0.6%)
 Embryo transfer 43 (0.0%) 2 (0.0%)
In vitro fertilization 1826 (0.9%) 87 (1.3%)
 Intracytoplasmic sperm injection 1973 (1.0%) 95 (1.5%)
 Other treatment 152 (0.1%) 7 (0.1%)
Pregnancy lossd 25 119 (12.5%) 1059 (16.4%)
Induced abortion 35 815 (17.9%) 1471 (22.8%)
Obesity 13 951 (7.0%) 1024 (15.9%)
a

Women having either infertility diagnoses or undergoing medically assisted reproduction.

b

Strict clinical infertility diagnosis, excluding women with polycystic ovary syndrome (PCOS) and endometriosis.

c

Last treatment/procedure registered.

d

Miscarriage, ectopic pregnancy or molar pregnancy.