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. 2022 Oct 10;37(12):2932–2941. doi: 10.1093/humrep/deac216

Table II.

Crude and adjusted risk ratios (RRs) and CIs of reproductive outcomes among women with any reproductive healthcare visit.

No asthma
Asthma
Active asthma a
No asthma (n = 200 248) Asthma (n = 6445) Crude RR (95% CI) Adjusted RRb (95% CI) Active asthma (n = 3560) Crude RR (95% CI) Adjusted RRb (95% CI)
Childbirth 164 979 (82.4%) 5329 (82.7%) 1.03 (1.02–1.04) 1.02 (1.01–1.03) 2892 (81.2%) 1.00 (0.99–1.02) 1.01 (0.99–1.02)
Infertility (diagnosis or treatment)c 16 220 (8.1%) 712 (11.0%) 1.26 (1.18–1.34) 1.29 (1.21–1.39) 372 (10.4%) 1.17 (1.07–1.28) 1.24 (1.13–1.37)
Childbirth after infertilityd 7599 (3.8%) 356 (5.5%) 1.08 (1.02–1.14) 1.05 (0.99–1.11) 178 (5.0%) 1.05 (0.97–1.14) 1.03 (0.95–1.12)
Pregnancy losse 25 119 (12.5%) 1059 (16.4%) 1.17 (1.11–1.22) 1.21 (1.15–1.28) 601 (16.9%) 1.22 (1.15–1.31) 1.25 (1.17–1.33)
Induced abortion 35 815 (17.9%) 1471 (22.8%) 1.14 (1.11–1.18) 1.15 (1.11–1.20) 847 (23.8%) 1.23 (1.17–1.30) 1.20 (1.14–1.26)
a

Defined as healthcare visit with asthma as main diagnosis <3 years before reproductive start-age.

b

Adjusted for obesity, endometriosis, polycystic ovary syndrome, approximated age of reproductive start and calendar year.

c

Includes women with healthcare visits for infertility (endometriosis and polycystic ovary syndrome excluded) or medically assisted reproduction without valid diagnosis.

d

Compared only to women with a healthcare visit for infertility or medically assisted reproduction, total n = 16 932. Total n = 16 592, when only active asthma included.

e

That is miscarriage, ectopic pregnancy or molar pregnancy.