TABLE 1.
Baseline characteristics of the cancer cases and matched controls.
| Variables | Controls (n = 1,389) | Cases (n = 1,389) | p-value |
| Age, y | 69.32 ± 7.76 | 69.32 ± 7.76 | 0.999 |
| Males, n (%) | 779 (56.08) | 779 (56.08) | 1.000 |
| BMI, kg/m2 | 25.73 ± 3.60 | 25.72 ± 3.83 | 0.953 |
| Baseline SBP, mmHg | 148.48 ± 21.26 | 147.52 ± 21.30 | 0.237 |
| Baseline DBP, mmHg | 83.73 ± 11.33 | 83.07 ± 11.76 | 0.134 |
| ALT, U/L | 8.05 (7.0, 13.0) | 10.0 (7.0, 14.0) | 0.148 |
| ALB, g/L | 45.43 ± 2.45 | 44.75 ± 2.97 | < 0.001 |
| TG, mmol/L | 1.21 (0.86, 1.77) | 1.19 (0.84, 1.80) | 0.630 |
| TC, mmol/L | 6.51 ± 1.23 | 6.44 ± 1.30 | 0.202 |
| UA, μmol/L | 320.0 (269.0, 371.0) | 314.0 (264.0, 374.0) | 0.393 |
| HDL-C, mmol/L | 1.23 ± 0.24 | 1.22 ± 0.27 | 0.795 |
| FBG, mmol/L | 6.25 ± 1.71 | 6.29 ± 1.83 | 0.626 |
| Creatinine, μmol/L | 45.84 (27.03, 51.00) | 52.0 (10.0, 64.0) | 0.748 |
| Folate, ng/mL | 6.14 (4.03,9.66) | 6.11 (4.22, 10.12) | 0.466 |
| HCY, μmol/L | 12.01 (10.31, 14.66) | 12.25 (10.06, 15.03) | 0.886 |
| Arginine, μg/mL | 20.88 (17.34, 25.11) | 21.41 (17.94, 26.25) | 0.001 |
| Marital status, [married, n (%)] | 1144 (82.36) | 1178 (84.81) | 0.354 |
| High school education or above, n (%) | 108 (7.78) | 103 (7.42) | 0.720 |
| Current smoker, n (%) | 334 (24.05) | 401 (28.87) | 0.011 |
| Current drinker, n (%) | 388 (27.93) | 370 (26.64) | 0.359 |
| History of CKD, n (%) | 14 (1.01) | 25 (1.80) | 0.076 |
| History of CHD, n (%) | 0 (0) | 165 (11.88) | < 0.001* |
| History of stroke, n (%) | 0 (0) | 64 (4.61) | < 0.001* |
| Family history of cancer, n (%) | 47 (3.38) | 50 (3.60) | 0.918 |
| Poor sleep quality, n (%) | 191 (13.75) | 259 (18.65) | 0.002 |
| Antihypertensive drug usage, n (%) | 494 (35.57) | 557 (40.10) | 0.014 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; ALT, alanine aminotransferase; ALB, albumin; TG, triglycerides; TC, total cholesterol; UA, uric acid; HDL-C, high-density lipoprotein cholesterol; FBG, fasting blood glucose; HCY, homocysteine; CKD, chronic kidney disease; CHD, coronary heart disease. *Compared by Fisher’s exact test.