TABLE 1.
The effect of various ICAM-1ref and ICAM-1Kilifi concentrations and inflow shear stress levels on the velocity of rolling PRBC
| Flow rate (Pa) | Receptor concentration (μg/ml) | Velocity (μm/s)a of PBRC infected by:
|
|||
|---|---|---|---|---|---|
| A4
|
ItG
|
||||
| ICAM-1ref | ICAM-1Kilifi | ICAM-1ref | ICAM-1Kilifi | ||
| 0.05 | 17.5 | 14.9 ± 1.5 | 130.2 ± 10.2 | 7 ± 1.6 | 2.1 ± 0.3 |
| 7 | 15.1 ± 0.6 | 125.8 ± 12.6 | 4 ± 0.3 | 3.7 ± 0.6 | |
| 0.7 | 160 ± 25.6 | 24 ± 2.8 | 251.2 ± 108.2 | ||
| 0.1 | 17.5 | 16.4 ± 2.5 | 116.5 ± 23.8 | 5 ± 1.8 | 2.7 ± 0.9 |
| 7 | 13.1 ± 1 | 75.5 ± 12.3 | 4.2 ± 0.8 | 3.7 ± 0.9 | |
| 0.7 | |||||
a
Experimental details are given in Materials and Methods, and values are the means ± standard errors of the results of 3 to 10 experiments.