Fig. 1.

Observed geometric mean change in CRP and observed mean change in bodyweight from baseline to week 68. Observed data for the in-trial period (time from randomisation to last contact with the trial site, regardless of treatment discontinuation or rescue intervention) for the full analysis set. Error bars represent the standard error of the mean. Changes from baseline in CRP are based on observed ratios to baseline. They are presented as observed percent changes converted using the formula (observed ratio − 1) × 100. CRP, C-reactive protein. Novo Nordisk data published in refs.13, 14, 15