Images in a 63-year-old woman with extensive small cell lung cancer
detected at screening CT. (A) Baseline whole-body PET scan
(left) and fused axial PET/CT images (right) demonstrate
fluorodeoxyglucose-avid right lower lobe nodule (arrowhead, whole-body
PET scan) and mediastinal and hilar lymphadenopathy (fused axial image
on top right) as well as left adrenal lesion (arrow, fused axial image
on bottom right). First-line therapy with the programmed death-ligand 1
inhibitor atezolizimab was initiated. (B) Follow-up
whole-body PET scan (left) and fused axial PET/CT images (right)
obtained after four cycles of atezolizimab, carboplatin, and etoposide
show significantly improved thoracic lymphadenopathy and resolution of
right lower lobe nodule. However, the left adrenal metastasis (arrow)
has progressed and was treated with radiation therapy.