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. 2022 Aug 4;107(12):2944–2949. doi: 10.3324/haematol.2022.280740

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Figure 1. — Kinetics of transcript aligned on international scale (BCR::ABL1/ABL1^IS). (A) Patient 1, (B) patient 2, (C) patient 3, (D) patient 4 (E) patient 4 and (F) patient 6. Months (M) corresponding to the dates from which transcript was aligned on international scale, treatment discontinuation, blast crisis, and last molecular follow-up from chronic phase chronic myeloid leukemia (CP-CML) diagnosis are indicated on the x axis. IM: Imatinib; D: Dasatinib; N: Nilotinib; IFN: interferon; Ara-C: Cytarabine; Allo-SCT: allogeneic stem cell transplantation; auto-SCT: autologous stem cell transplantation; AP: accelerated phase; LBC: lymphoid blast crisis; MBC: myeloid blast crisis; MMR: major molecular response; DMR: deep molecular response (i.e., MR4 and MR4.5).