Table 1. Underestimated status of the main BDs in Shaanxi Province, 2014–2020.
| Item | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | |||||||||||||||||||||
| ≥28 weeks | Total |
Under-
estimated (%) |
≥28 weeks | Total |
Under-
estimated (%) |
≥28 weeks | Total |
Under-
estimated (%) |
≥28 weeks | Total |
Under-
estimated (%) |
≥28 weeks | Total |
Under-
estimated (%) |
≥28 weeks | Total |
Under-
estimated (%) |
≥28 weeks | Total |
Under-
estimated (%) |
||||||||
| Note: Perinatal prevalence (the number of cases of 28 or more gestational weeks per 10,000 births), total prevalence (the number of cases regardless of gestational age per 10,000 births) and underestimated proportion (cases before 28 gestational weeks accounting for all cases) of birth defects were calculated. Abbreviation: BD=birth defect; NTDs=neural tube defects; CHDs=congenital heart defects. | ||||||||||||||||||||||||||||
| NTDs | 5.4 | 16.0 | 66.2 | 3.4 | 12.0 | 71.6 | 2.5 | 12.8 | 80.4 | 2.2 | 12.6 | 82.5 | 1.0 | 11.8 | 91.5 | 0.9 | 6.8 | 86.8 | 1.7 | 11.6 | 85.4 | |||||||
| Hydrocephalus | 7.5 | 13.3 | 43.6 | 4.8 | 10.4 | 54.0 | 4.8 | 8.0 | 39.8 | 4.2 | 8.3 | 49.3 | 3.4 | 6.6 | 48.3 | 2.5 | 4.6 | 45.1 | 3.3 | 6.7 | 50.4 | |||||||
| Cleft palate | 1.0 | 1.3 | 21.5 | 2.2 | 2.6 | 14.3 | 2.5 | 3.0 | 15.6 | 2.2 | 2.6 | 14.1 | 2.7 | 3.0 | 11.1 | 2.3 | 2.3 | −1.0 | 3.0 | 3.8 | 21.6 | |||||||
| Cleft lip with or without palate | 6.7 | 14.3 | 53.1 | 6.2 | 16.4 | 62.3 | 5.4 | 16.1 | 66.4 | 4.9 | 21.5 | 77.2 | 5.4 | 22.7 | 76.2 | 3.4 | 17.8 | 80.9 | 3.3 | 20.0 | 83.5 | |||||||
| Anotia/microtia | 2.0 | 2.0 | −0.9 | 1 | 1.5 | 35.1 | 0.7 | 0.7 | −2.4 | 1.6 | 1.7 | 6.3 | 1.0 | 1.3 | 21.0 | 1.5 | 1.7 | 12.2 | 1.1 | 1.4 | 22.3 | |||||||
| Other deformities of the outer ear | 2.4 | 2.4 | 0.3 | 4.5 | 4.6 | 2.6 | 4.1 | 4.1 | 0.1 | 2.6 | 2.6 | −1.5 | 2.5 | 2.7 | 5.9 | 3.5 | 3.8 | 6.9 | 5.4 | 5.5 | 2.3 | |||||||
| Esophagus atresia/stenosis | 1.8 | 2.3 | 20.5 | 1.2 | 1.5 | 22.1 | 2.1 | 2.3 | 7.9 | 0.7 | 1.1 | 36.2 | 0.6 | 0.9 | 32.3 | 1.0 | 1.3 | 20.2 | 1.8 | 2.0 | 9.2 | |||||||
| Anorectal atresia/stenosis | 2.0 | 2.4 | 16.9 | 1.9 | 2.2 | 14.6 | 2.3 | 2.5 | 8.3 | 2.0 | 2.2 | 8.9 | 3.2 | 3.2 | −1.1 | 1.8 | 2.4 | 24.7 | 2.1 | 2.7 | 22.0 | |||||||
| Hypospadias | 2.6 | 2.7 | 3.3 | 3.8 | 3.8 | −0.9 | 4.0 | 4.1 | 2.5 | 6.2 | 6.2 | 0.3 | 5.8 | 6.1 | 4.5 | 4.2 | 4.6 | 7.8 | 5.2 | 5.2 | 0.8 | |||||||
| Club foot | 2.7 | 4.2 | 36.4 | 3.1 | 6.5 | 52.3 | 1.8 | 4.8 | 62.4 | 1.6 | 4.0 | 60.2 | 1.8 | 4.3 | 58.2 | 3.0 | 5.4 | 43.9 | 2.0 | 4.4 | 54.5 | |||||||
| Polydactyly | 13.6 | 13.9 | 2.0 | 15.4 | 15.6 | 1.2 | 14.4 | 14.9 | 3.6 | 13.5 | 14.3 | 5.4 | 16.5 | 17.2 | 4.4 | 13.6 | 15.0 | 9.9 | 18.8 | 19.7 | 4.3 | |||||||
| Syndactyly | 4.1 | 4.1 | 0.1 | 2.9 | 3.3 | 10.8 | 4.3 | 4.6 | 5.7 | 5.5 | 5.6 | 1.9 | 6.0 | 6.5 | 7.8 | 6.4 | 7.3 | 12.5 | 7.1 | 7.4 | 3.9 | |||||||
| Limb reduction defects | 2.0 | 3.4 | 41.1 | 2.6 | 4.1 | 36.7 | 1.6 | 3.6 | 56.1 | 1.2 | 5.1 | 76.6 | 1.0 | 4.3 | 76.8 | 1.0 | 3.8 | 73.4 | 1.7 | 4.7 | 63.6 | |||||||
| Congenital diaphragmatic hernia | 1.7 | 3.0 | 42.8 | 1.4 | 3.3 | 57.0 | 1.0 | 1.9 | 48.4 | 0.6 | 1.5 | 59.0 | 0.9 | 2.4 | 62.6 | 1.5 | 3.3 | 54.6 | 0.9 | 2.5 | 64.7 | |||||||
| Omphalocele | 0.1 | 0.4 | 76.5 | 0 | 1.2 | 100.0 | 0.6 | 1.5 | 59.5 | 1.0 | 2.7 | 62.7 | 0.6 | 3.3 | 80.9 | 1.0 | 3.6 | 72.6 | 0.3 | 4.5 | 93.4 | |||||||
| Gastroschisis | 0.9 | 2.1 | 57.6 | 0 | 3.1 | 100.0 | 0.1 | 1.3 | 92.0 | 0.4 | 2.0 | 79.5 | 0.3 | 1.0 | 75.3 | 0.0 | 0.7 | 100.0 | 0.3 | 2.1 | 85.9 | |||||||
| Down syndrome | 1.7 | 3.5 | 52.0 | 1.7 | 5.3 | 68.0 | 1.4 | 6.7 | 79.2 | 1.3 | 12.6 | 89.6 | 1.7 | 12.8 | 86.7 | 1.7 | 11.6 | 85.4 | 0.9 | 12.2 | 92.6 | |||||||
| CHDs | 82.3 | 92.7 | 11.3 | 97.2 | 112.8 | 13.8 | 54.8 | 68.7 | 20.3 | 64.8 | 82.4 | 21.4 | 108.5 | 137.2 | 20.9 | 79.6 | 104.8 | 24.0 | 128.1 | 155.0 | 17.3 | |||||||