Table 2. The ranking for top 10 most common BDs in Shaanxi Province, 2014–2020.
| Rank | Perinatal prevalence (1/10,000) | Total prevalence (1/10,000) | ||||||||||||||
| 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | |||
| Note: Perinatal prevalence (cases of 28 or more gestational weeks), total prevalence (all cases regardless of gestational age) and underestimated proportion (cases before 28 gestational weeks accounting for all cases) of birth defects were calculated. Abbreviation: BD=birth defect; NTDs=neural tube defects; CHDs=congenital heart defects. | ||||||||||||||||
| 1 | CHDs (82.3) | CHDs (97.2) | CHDs (54.8) | CHDs (64.8) | CHDs (108.5) | CHDs (79.6) | CHDs (128.1) | CHDs (92.8) | CHDs (112.8) | CHDs (68.7) | CHDs (82.5) | CHDs (137.2) | CHDs (104.8) | CHDs (155.0) | ||
| 2 | Polydactyly (13.6) | Polydactyly (15.4) | Polydactyly (14.4) | Polydactyly (13.5) | Polydactyly (16.5) | Polydactyly (13.6) | Polydactyly (18.8) | NTDs (16.0) | Cleft lip with or without palate (16.4) | Cleft lip with or without palate (16.1) | Cleft lip with or without palate (21.5) | Cleft lip with or without palate (22.6) | Cleft lip with or without palate (17.7) | Cleft lip with or without palate (20.0) | ||
| 3 | Hydrocephalus (7.5) | Cleft lip with or without palate (6.2) | Cleft lip with or without palate (5.4) | Hypospadias (6.2) | Syndactyly (6.0) | Syndactyly (6.4) | Syndactyly (7.1) | Cleft lip with or without palate (14.3) | Polydactyly (15.6) | Polydactyly (14.9) | Polydactyly (14.3) | Polydactyly (17.3) | Polydactyly (15.1) | Polydactyly (19.7) | ||
| 4 | Cleft lip with or without palate (6.7) | Hydrocephalus (4.8) | Hydrocephalus (4.8) | Syndactyly (5.5) | Hypospadias (5.8) | Hypospadias (4.2) | Other deformities of the outer ear (5.4) | Polydactyly (13.9) | NTDs (12.0) | NTDs (12.8) | NTDs (12.6) | Down syndrome (12.8) | Down syndrome (11.6) | Down syndrome (12.2) | ||
| 5 | NTDs (5.4) | Other deformities of the outer ear (4.5) | Syndactyly (4.3) | Cleft lip with or without palate (4.9) | Cleft lip with or without palate (5.4) | Other deformities of the outer ear (3.5) | Hypospadias (5.2) | Hydrocephalus (13.3) | Hydrocephalus (10.4) | Hydrocephalus (8.0) | Down syndrome (12.6) | NTDs (11.8) | Syndactyly (7.3) | NTDs (11.6) | ||
| 6 | Syndactyly (4.1) | Hypospadias (3.8) | Other deformities of the outer ear (4.1) | Hydrocephalus (4.2) | Hydrocephalus (3.4) | Cleft lip with or without palate (3.4) | Cleft lip with or without palate (3.3) | Club foot (4.2) | Club foot (6.5) | Down syndrome (6.7) | Hydrocephalus (8.3) | Hydrocephalus (6.6) | NTDs (6.8) | Syndactyly (7.4) | ||
| 7 | Club foot (2.7) | NTDs (3.4) | Hypospadias (4.0) | Other deformities of the outer ear (2.6) | Anorectal atresia stenosis (3.2) |
Club foot (3.0) | Cleft palate (3.0) | Syndactyly (4.1) | Down syndrome (5.3) | Club foot (4.8) | Hypospadias (6.2) | Syndactyly (6.5) | Club foot (5.4) | Hydrocephalus (6.7) | ||
| 8 | Hypospadias (2.6) | Club foot (3.1) | NTDs (2.5) | NTDs (2.2) | Cleft palate (2.7) | Hydrocephalus (2.5) | Anorectal atresia/ stenosis (2.1) |
Down syndrome (3.5) | Other deformities of the outer ear (4.6) | Syndactyly (4.6) | Syndactyly (5.6) | Hypospadias (6.1) | Hydrocephalus (4.6) | Other deformities of the outer ear (5.5) | ||
| 9 | Other deformities of the outer ear (2.4) | Syndactyly (2.9) | Anorectal atresia/ stenosis (2.3) |
Anorectal atresia/ stenosis (2.0) |
Other deformities of the outer ear (2.5) | Cleft palate (2.3) | Club foot (2.0) | limb reduction defects (3.4) | limb reduction defects (4.1) | Other deformities of the outer ear (4.1) | limb reduction defects (5.1) | Club foot (4.3) | Hypospadias (4.6) | Hypospadias (5.2) | ||
| 10 | Anorectal atresia/ stenosis (2.0) |
Limb reduction defects (2.6) | Esophagus atresia/ stenosis (2.1) |
Club foot (1.6) | Club foot (1.8) | Anorectal atresia/ stenosis (1.8) |
Esophagus atresia/ stenosis (1.8) |
Congenital diaphragmatic hernia (3.0) | Hypospadias (3.8) | Hypospadias (4.1) | Club foot (4.0) | limb reduction defects (4.3) | Other deformities of the outer ear (3.8) | Limb reduction defects (4.7) | ||