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. 2022 Dec 1;12(53):34531–34547. doi: 10.1039/d2ra05076e

Bioactivity of antivibrio compounds isolated from marine fungi.

No. Compounds Sources Antivibrio activities Mechanism of action Ref.
1 6-Hydroxylpaspaline (32) Penicillium sp. AS-79 V. parahaemolyticus MIC 64.0 μg mL−1 Inhibition of the growth 74
2 Paspalitrem C (33) Penicillium sp. AS-79 V. parahaemolyticus MIC 8.0 μg mL−1, V. alginolyticus MIC 4 μg mL−1 Inhibition of the growth 74
3 Emindole SB (34) Penicillium sp. AS-79 V. parahaemolyticus MIC 2.0 μg mL−1, V. alginolyticus MIC 1 μg mL−1 Inhibition of the growth 74
4 3-Deoxo-4b-deoxypaxilline (35) Penicillium sp. AS-79 V. parahaemolyticus MIC 16.0 μg mL−1 Inhibition of the growth 74
5 10,23 Dihydro-24,25-dehydroaflavinine (36) Penicillium sp. AS-79 V. parahaemolyticus MIC 0.5 μg mL−1, V. alginolyticus MIC 0.5 μg mL−1 Inhibition of the growth 74
6 Penijanthine C (37) Penicillium janthinellum V. anguillarum MIC 3.1 μM, V. parahaemolyticus MIC 6.3 μM, V. alginolyticus MIC 3.1 μM Inhibition of the growth 75
7 Penijanthine D (38) Penicillium janthinellum V. anguillarum MIC 12.5 μM, V. parahaemolyticus MIC 12.5 μM, V. alginolyticus MIC 12.5 μM Inhibition of the growth 75
8 Penijanthoid A (39) Penicillium janthinellum Vibrio spp. MICs 25.0–50.0 μM Inhibition of the growth 75
9 Penijanthoid B (40) Penicillium janthinellum Vibrio spp. MICs 25.0–50.0 μM Inhibition of the growth 75
10 Aspergixanthone I (41) Aspergillus sp. ZA-01 V. parahaemolyticus MIC 1.56 μM, V. anguillarum MIC 1.56 μM, V. alginolyticum MIC 3.12 μM Inhibition of the growth 76
11 Aspergixanthone J (42) Aspergillus sp. ZA-01 V. parahaemolyticus MIC 6.25 μM, V. anguillarum MIC 25 μM, V. alginolyticum MIC 25 μM Inhibition of the growth 76
12 Aspergixanthone K (43) Aspergillus sp. ZA-01 V. parahaemolyticus MIC 3.12 μM, V. anguillarum MIC 25 μM, V. alginolyticum MIC 12.5 μM Inhibition of the growth 76
13 Aspergixanthone A (44) Aspergillus sp. ZA-01 V. parahaemolyticus MIC 25 μM, V. anguillarum MIC 25 μM, V. alginolyticum MIC 25 μM Inhibition of the growth 76
14 15-Acetyl tajixanthone hydrate (45) Aspergillus sp. ZA-01 V. parahaemolyticus MIC 12.5 μM, V. anguillarum MIC 25 μM, V. alginolyticum MIC 12.5 μM Inhibition of the growth 76
15 Tajixanthone hydrate (46) Aspergillus sp. ZA-01 V. parahaemolyticus MIC 6.25 μM, V. anguillarum MIC 6.25 μM, V. alginolyticum MIC 12.5 μM Inhibition of the growth 76
16 16-Chlorotajixanthon (47) Aspergillus sp. ZA-01 V. parahaemolyticus MIC 25 μM, V. anguillarum MIC 6.25 μM, V. alginolyticum MIC 25 μM Inhibition of the growth 76
17 Terreprenphenol A (48) Aspergillus terreus EN-539 V. harveyi MIC 4 μg mL−1, V. parahemolyticus MIC 8 μg mL−1, V. vulnificus MIC 32 μg mL−1 Inhibition of the growth 77
18 4-Hydroxy-3-prenybenzoic acid (49) Aspergillus terreus EN-539 V. harveyi MIC 32 μg mL−1, V. parahemolyticus MIC 8 μg mL−1 Inhibition of the growth 77
19 4-Hydroxy-3-(3-methyl-but-2-enyl)-benzaldehyde (50) Aspergillus terreus EN-539 V. harveyi MIC 8 μg mL−1, V. parahemolyticus MIC 8 μg mL−1, V. vulnificus MIC 64 μg mL−1 Inhibition of the growth 77
20 Bisabolene sesquiterpenoid (51) Aspergillus versicolor SD-330 V. harveyi MIC 4 μg mL−1, V. parahemolyticus MIC 16 μg mL−1 Inhibition of the growth 78
21 Aspergoterpenin C (52) Aspergillus versicolor SD-330 V. harveyi MIC 8 μg mL−1, V. parahemolyticus MIC 8 μg mL−1 Inhibition of the growth 78
22 (7S,11S)-(þ)-12-Hydroxysydonic acid (53) Aspergillus versicolor SD-330 V. anguillarum MIC 32 μg mL−1, V. harveyi MIC 16 μg mL−1, V. parahemolyticus MIC 32 μg mL−1 Inhibition of the growth 78
23 (S)-(þ)-11-Dehydrosydonic acid (54) Aspergillus versicolor SD-330 V. anguillarum MIC 32 μg mL−1, V. harveyi MIC 32 μg mL−1 Inhibition of the growth 78
24 Engyodontiumone I (55) Aspergillus versicolor SD-330 V. harveyi MIC 4 μg mL−1, V. parahemolyticus MIC 8 μg mL−1 Inhibition of the growth 78
25 Trypacidin (56) Aspergillus fumigatus HX-1 V. harveyi MIC 31.25 μg mL−1 Inhibition of the growth 79
26 Paraconthone A (57) Paraconiothyrium sp. V. anguillarum & V. parahemolyticus, MIC 30 μg mL−1 Inhibition of the growth 80
27 Botryosphaerone (58) Paraconiothyrium sp. V. anguillarum & V. parahemolyticus, MIC 30 μg mL−1 Inhibition of the growth 80
28 O-Methylaspmenone (59) Paraconiothyrium sp. V. anguillarum & V. parahemolyticus, MIC 30 μg mL−1 Inhibition of the growth 80
29 Acremocholone (60) Acremonium sp. NBUF150 V. scophthalmi MIC 8 μg mL−1, V. shiloni MIC 8 μg mL−1, V. brasiliensis MIC 8 μg mL−1 Inhibition of the growth 81