TABLE 4.
Heterogeneity and horizontal pleiotropy check.
EP | OC | Heterogeneity check 1 | Heterogeneity check 2 | Horizontal pleiotropy check | ||||
---|---|---|---|---|---|---|---|---|
Q | P | Q | P | Intercept | SE | P | ||
BPH | BLCA | 7.613744 | 0.47208 | 5.508447 | 0.598165 | -0.00052 | 0.000357 | 0.190081 |
BLCA | BPH | 34.51226 | 0.00056 | 33.85226 | 0.000382 | 0.000309 | 0.000667 | 0.652321 |
Benign prostate hyperplasia, BPH; bladder cancer, BLCA; exposure, EP; outcome, OC; Heterogeneity check one was performed by IVW, method; Cochran’s Q value, Q; Heterogeneity check two was performed by MR-Egger method; Horizontal pleiotropy test was performed by MR-Egger method; inverse variance weighted, IVW; standard error, SE.