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. 2022 Nov 21;25(1):17. doi: 10.3892/ol.2022.13603

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Copyright: © Okubo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Receiver operating characteristic analysis of the thyroid receiving doses associated with the development of hypothyroidism after radiotherapy for early glottic carcinoma. The AUCs for V5Gy, V10Gy, V20Gy, V30Gy, V40Gy, V50Gy, V60Gy and V65Gy are shown. (A) V5Gy, 0.711 (95% CI, 0.558-0.865); (B) V10Gy, 0.705 (95% CI, 0.554-0.857); (C) V20Gy, 0.695 (95% CI, 0.541-0.850); (D) V30Gy, 0.690 (95% CI, 0.535-0.845); (E) V40Gy, 0.684 (95% CI, 0.528-0.841); (F) V50Gy, 0.684 (95% CI, 0.531-0.838); (G) V60Gy, 0.686 (95% CI, 0.536-0.846); and (H) mean thyroid dose, 0.692 (95% CI, 0.537-0.847). The AUC value was the highest for V5Gy. The cutoff value of V5Gy was 44.8%, with a sensitivity of 73.3% and a specificity of 50.0%. AUC, area under the receiver operating characteristic curve. Vx Gy, irradiated underlying thyroid volumes of more than × Gy.