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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Biosens Bioelectron. 2022 Mar 9;207:114136. doi: 10.1016/j.bios.2022.114136

Fig. 6.

Fig. 6.

Analysis of beating velocity and calcium signal propagation of one representative hHO. (A) Representative frame of hHO beating recorded by OCT. Red arrows represent motion vectors. The direction and size of each arrow represents the direction and magnitude of the motion vector, respectively. (B) Average absolute beating velocity of the whole recording. Magenta arrows indicate locations with fewer detected motions. (C) Representative traces of beating velocity over time. Contraction and relaxation are marked with red triangles and green circles, respectively. In panels A–C, B-scans on left and right are orthogonal (supplementary video 7). (D) A heatmap depicting initiation of calcium transients of each pixel within the heart organoid. Scale bars: 200 μm.