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. 2022 Nov 17;13:1050093. doi: 10.3389/fphar.2022.1050093

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Copyright © 2022 Li, Zhou, Luo, Tao, Zhang, Zhao, Lin, Zeng and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of circRNAs in human HF tissues (A)Principal component analysis (B) Box plot (C) Density plot (D) Differential circRNAs volcano plot. The abscissa is the log2 (Fold Change), and the ordinate is -log10 (p-value). circRNAs with fold changes ≥2 and p-values ≤ 0.05 are indicated as significant up-regulation (E) GO_enrichment_scatterplot of the parental genes of the upregulated circRNAs (F) KEGG_enrichment_scatterplot of the parental genes of the upregulated circRNAs.C represents HF samples (n = 6). N represents control samples (n = 3).