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Concentration of the four most abundant bromo-spiroisoxazolines in the EM extracts for each set of reproduced experiments (n = 3 for CAPT1 and CAPT2) compared to their concentration in the sponge crude extract. The results are expressed as the proportion of weight/weight (w/w) in ppm and in percentage of dried sponge biomass for EM and crude, respectively. The quantities of all four metabolites in their respective extract are expressed in % w/w, below each bar graph.
