Table 3.
Diagnostic performance of ANNE sleep vs PSG at AHI thresholds.
| AHI Cutoff (events/h) | Sensitivity (95% CI) | Specificity (95% CI) | AUC (95% CI) | Accuracy | PPV (95% CI) | NPV (95% CI) | LR+ | LR− |
|---|---|---|---|---|---|---|---|---|
| 5 | 0.96 (0.92–0.99) | 0.86 (0.77–0.92) | 0.91 (0.87– 0.95) | 0.92 | 0.91 (0.85–0.95) | 0.94 (0.87–0.98) | 6.7 | 0.04 |
| 15 | 0.90 (0.8–0.96) | 0.97 (0.94–0.99) | 0.94 (0.90–0.97) | 0.95 | 0.94 (0.85–0.98) | 0.96 (0.91–0.98) | 35.2 | 0.11 |
| 30 | 0.65 (0.45–0.81) | 0.99 (0.96–0.99) | 0.82 (0.73–0.90) | 0.94 | 0.91 (0.71–0.99) | 0.95 (0.91–0.97) | 62.6 | 0.36 |
AHI = apnea-hypopnea index, AUC = area under the curve, CI = confidence interval, LR = likelihood ratio, NPV = negative predictive value, PPV = positive predictive value, PSG = polysomnography.