Table 1.

Clinical outcomes.

	Baseline	Day 10	Day 20	Day 50
PSQI total score	20	14	9	8
Sleep quality	3	2	1	1
Sleep latency	3	2	1	0
Sleep duration	3	2	1	1
Sleep efficiency	3	2	2	2
Sleep disturbance	2	1	1	1
Sleep medication	3	3	2	2
Daytime dysfunction	3	2	1	1
HAMA score	38	22	14	15
HAMD score	37	25	14	12
Polysomnography
Sleep continuity
Sleep-onset latency (SOL), min	41	35.9	21.5	27
Total sleep time (TST), min	420	431	502.5	521
Sleep efficiency, %	65.4	67.8	82.9	87.7
Apnea-hypopnea index (AHI), events/h	8.6	5.1	5.2	4.6
Sleep architecture, % of total sleep time
Stage 1 sleep	15.1	5.5	10	5.4
Stage 2 sleep	70.2	80.9	65.9	81.7
Slow-wave sleep	6.1	1.4	2.2	4.7
REM sleep	8.6	12.3	21.9	8.3
REM sleep parameters
REM latency, min	214.5	221.5	116.5	111

HAMA = Hamilton Anxiety Scale, HAMD = Hamilton Depression Scale, PSQI = Pittsburgh Sleep Quality Index, REM = rapid eye movement.