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. 2022 Dec 1;18(12):2763–2774. doi: 10.5664/jcsm.10210

Table 5.

Mediation models.

Model Treatment Component (Action Theory) (Conceptual Theory) Total Effect (a × b + c) (Mediation)
Path a Path b Indirect Effect
Outcome-> COPD Self-Efficacy Insomnia Severity Insomnia Severity
1. COPD Self-Efficacy and Insomnia Severity COPD-ED −6.2 (4.4) 0.08 (0.03)* −1.8 (1.3) −0.49 (0.39)
CBT-I −2.7 (4.2) −4.7 (1.2)* −0.22 (0.35)
COPD-ED × CBT-I 5.9 (6.1) 2.6 (1.7) 0.47 (0.52)
Outcome-> Sleep Self-Efficacy Insomnia Severity Insomnia Severity
2. Sleep Self-Efficacy and Insomnia Severity COPD-ED 0.97 (1.8) −0.47 (0.06)* −1.5 (1.3) −0.46 (0.84)
CBT-I 2.2 (1.7) −4.5 (1.2)* −1.0 (0.82)
COPD-ED × CBT-I −0.31 (2.4) 2.1 (1.8) 0.14 (1.1)
Outcome-> Beliefs and Attitudes about Sleep Insomnia Severity Insomnia Severity
3. Beliefs and Attitudes about Sleep and Insomnia Severity COPD-ED −0.75 (0.35)* 1.2 (0.35)* −2.0 (1.3) 0.90 (0.49)
CBT-I −0.88 (0.33)* −4.8 (1.2)* −1.05 (0.50)*
COPD-ED × CBT-I 0.64 (0.48) 2.7 (1.8) 0.77 (0.62)
Outcome-> CRQ Emotional Function Insomnia Severity Insomnia Severity
4. CRQ Emotional Function and Insomnia Severity COPD-ED 0.37 (0.21) −1.9 (0.57)* −1.8 (1.3) −0.72 (0.46)
CBT-I 0.45 (0.21)* −5.0 (1.2)* 0.87 (0.47)
COPD-ED × CBT-I 0.56 (0.29) 2.5 (1.8) 1.1 (0.65)
Outcome-> COPD Self-Efficacy Fatigue Fatigue
5. COPD Self-Efficacy and CRQ Fatigue COPD-ED −6.2 (4.4) −0.01 (0.001)* 0.16 (0.23) 0.07 (0.06)
CBT-I −2.7 (4.2) 0.44 (0.22)* 0.03 (0.05)
COPD-ED × CBT-I 5.9 (6.1) −0.43 (0.31) −0.07 (0.08)
Outcome-> Sleep Self-Efficacy Fatigue Fatigue
6. Sleep Self-Efficacy and CRQ Fatigue COPD-ED 0.97 (1.8) 0.03 (0.01)* 0.18 (0.23) 0.03 (0.05)
CBT-I 2.2 (1.7) 0.46 (0.22)* 0.07 (0.06)
COPD-ED × CBT-I −0.31 (2.4) −0.42 (0.31) −0.01 (0.07)
Outcome-> Beliefs and Attitudes about Sleep Fatigue Fatigue
7. Belief and Attitudes about Sleep and CRQ Fatigue COPD-ED −0.75 (0.35)* −0.09 (0.06) 0.29 (0.22) 0.07 (0.06)
CBT-I −0.88 (0.33)* 0.51 (0.21)* 0.08 (0.06)
COPD-ED × CBT-I 0.64 (0.48) 0.58 (0.31) −0.06 (0.06)
Outcome-> CRQ Emotional Function Fatigue Fatigue
8. CRQ Emotional Function and CRQ Fatigue COPD-ED 0.37 (0.21) 0.44 (0.10)* 0.18 (0.23) 0.16 (0.10)
CBT-I 0.45 (0.21)* 0.49 (0.22)* 0.20 (0.10)
COPD-ED × CBT-I 0.56 (0.29) −0.46 (0.31) 0.25 (0.14)

All models are adjusted for baseline measures of the mediator and outcome. Cell values are parameter estimate (standard error). *P < .05. Italic: P < .10. -> = effects on variables in columns to the right, CBT-I = cognitive behavioral therapy for insomnia, COPD-ED = chronic obstructive pulmonary disease education, CRQ = Chronic Respiratory Disease Questionnaire.