Table 1.
Regional brain correlation (r) values between DTI measures, and AHI scores and SaO2 changes in patients with OSA.
| Brain Regions | MD vs AHI r (P-value) | AD vs AHI r (P-value) | RD vs AHI r (P-value) | MD vs SaO2 r (P-value) | AD vs SaO2 r (P-value) | RD vs SaO2 r (P-value) |
|---|---|---|---|---|---|---|
| L Insula | .65 (.005) | .66 (.004) | .65 (.005) | – | – | – |
| R Amygdala | .70 (.002) | .70 (.002) | .68 (.003) | – | – | – |
| L Amygdala | .70 (.002) | .71 (.001) | .69 (.002) | – | – | – |
| R Basal forebrain | .72 (.001) | .71 (.001) | .72 (.001) | – | – | – |
| L Basal forebrain | .68 (.003) | .69 (.002) | .68 (.003) | – | – | – |
| R Mid-cingulate | – | – | – | .68 (.003) | .67 (.003) | .68 (.003) |
| L Mid-cingulate | – | – | – | .67 (.003) | .64 (.006) | .68 (.003) |
| R Medial orbital gyrus | .74 (.001) | .73 (.001) | .74 (.001) | – | – | – |
| L Medial orbital gyrus | – | – | – | .68 (.003) | .67 (.003) | .69 (.002) |
| R Temporal pole | .79 (.0001) | .78 (.0001) | .79 (.0001) | .69 (.002) | .65 (.004) | .70 (.002) |
| L Temporal pole | .78 (.0001) | .76 (.0003) | .78 (.0001) | .70 (.002) | .68 (.003) | .70 (.002) |
| L Medial frontal cortex | .66 (.004) | .67 (.004) | .66 (.004) | .68 (.003) | .66 (.004) | .68 (.002) |
| R Middle temporal gyrus | – | – | – | .76 (.0004) | .71 (.001) | .79 (.0001) |
| L Middle temporal gyrus | .66 (.004) | .71 (.002) | .64 (.006) | .72 (.001) | .70 (.002) | .74 (.001) |
| Cerebellar cortices | .63 (.006) | .63 (.007) | .64 (.006) | – | – | – |
| Cerebellar vermis | – | – | – | .68 (.003) | .65 (.004) | .68 (.003) |
| Basal pons | .68 (.003) | .67 (.003) | .68 (.002) | – | – | – |
| R Putamen | – | – | – | .66 (.004) | – | .63 (.007) |
| L Putamen | –.69 (.002) | –.62 (.008) | –.64 (.006) | – | – | – |
| Parietal cortex | –.67 (.003) | –.59 (.013) | –.69 (.002) | – | – | – |
| Cerebellar cortices II | –.75 (.0001) | –.75 (.001) | –.73 (.001) | – | – | – |
| Occipital cortex | – | – | – | –.68 (.002) | –.66 (.004) | –.66 (.004) |
AD = radial diffusivity, L = left, MD = mean diffusivity, OSA = obstructive sleep apnea, R = right, RD = radial diffusivity.