Table 2.
Baseline mean ESAS symptom and subscale scores
| All Participants (n=430) | Patient (n=343) | Caregiver (n=87) | ||
|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | p-value* | |
| Pain | 2.87 (2.6) | 2.94 (2.6) | 2.51 (2.6) | 0.27 |
| Fatigue | 3.35 (2.5) | 3.57 (2.6) | 2.45 (2.3) | 0.0003 |
| Nausea | 0.66 (1.5) | 0.81 (1.7) | 0.07 (0.5) | <0.0001 |
| Depression | 1.44 (2.1) | 1.50 (2.2) | 1.23 (1.7) | 0.25 |
| Anxiety | 2.11 (2.4) | 2.09 (2.5) | 2.15 (2.1) | 0.85 |
| Appetite | 2.62 (2.8) | 2.94 (2.8) | 1.38 (2.3) | <0.0001 |
| Drowsiness | 1.81 (2.3) | 2.01 (2.4) | 1.04 (1.8) | 0.0006 |
| Shortness of breath | 0.95 (1.8) | 1.12 (1.9) | 0.23 (0.86) | <0.0001 |
| Sleep | 4.13 (2.6) | 4.22 (2.6) | 3.70 (2.6) | 0.09 |
| Well-being | 3.56 (2.4) | 3.71 (2.4) | 3.01 (2.3) | 0.015 |
| Spiritual Pain | 1.28 (2.1) | 1.31 (2.1) | 1.13 (2.0) | 0.54 |
|
| ||||
| GDS1 | 23.39 (14.9) | 24.77 (15.4) | 17.92 (11.5) | <0.0001 |
| PHS1 | 12.26 (9.2) | 13.38 (9.5) | 7.85 (6.4) | <0.0001 |
| PSS1 | 3.54 (4.1) | 3.58 (4.3) | 3.36 (3.3) | 0.66 |
1
GDS (Global distress score) equals sum of pain, fatigue, nausea, depression, anxiety, drowsiness, appetite, well-being, and shortness of breath (total score 0–90); PHS (physical distress score) equals sum of pain, fatigue, nausea, drowsiness, appetite, and shortness of breath (total 0–60); and PSS (psychological distress score) equals sum of depression and anxiety.
SD= Standard Deviation
*
p-values compare patients to caregivers using ANOVA