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. 2022 Dec 1;19:284. doi: 10.1186/s12974-022-02647-z

Fig. 5.

Fig. 5

Overexpression of circ_0001293 alleviates IL-1β-induced astrocyte inflammation by downregulating miR-8114. a, b RT–qPCR was used to determine the expression of circ_0001293 and miR-8114. c Cell viability was detected using the CCK-8 assay. d ELISAs were conducted to determine the levels of TNF-α, IFN-γ, IL-6, IL-10 and TGF-β2. **P < 0.01 and ***P < 0.001 compared with NC; ##P < 0.01 and ###P < 0.001 compared with IL-1β; &&&P < 0.001 compared with IL-1β + oe-circ. All values are presented as the means ± SD (n = 3)