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. 2022 Dec 1;10:205. doi: 10.1186/s40168-022-01402-z

Fig. 1.

Fig. 1

Experimental design. A The ruminal microbiota compositions and systemic inflammation in healthy (H) and mastitis cows were analyzed. B Ruminal microbiota transplantation (RMT) from cows to mice was performed to show the role of ruminal dysbiosis in the pathogenesis of mastitis. C Investigating whether and how low-grade endotoxemia contributes to the development of mastitis in mice. D Investigating whether impaired host anti-inflammatory enzyme by microbial dysbiosis deteriorates pathogen-induced mastitis in mice