Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 17;10:1050489. doi: 10.3389/fcell.2022.1050489

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Voynova, Kulebyakin, Grigorieva, Novoseletskaya, Basalova, Alexandrushkina, Arbatskiy, Vigovskiy, Sorokina, Zinoveva, Bakhchinyan, Kalinina, Akopyan, Tkachuk, Tyurin-Kuzmin and Efimenko.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Selected miRNAs differentially expressed in EVs secreted by control and senescent MSCs along with their targets. Interaction maps illustrated differently expressed miRNAs as edges and their potential target mRNA as nodes. Coloured miRNAs are shown if significantly reduced (red) or enhanced (blue) in MSC-EVs from aged donors compared to young ones. The degree of color saturation shows the value of the target score level (relative units). A more saturated color indicates a higher value, and therefore a high reliability of the relationship between the miRNA and its target.