Table 3.
Mean ± SD for biochemical analysis of serum hypertension indexes in different experiemntal groups.
| Items | Experimental groups | F value | p-value | |||||
|---|---|---|---|---|---|---|---|---|
| Control (n = 6) | Model (n = 6) | PRV 0.5 mg/kg (n = 6) | PRV1 mg/kg (n = 6) | PRV2 mg/kg (n = 6) | Losartan (n = 6) | |||
| Angiotensin II (ng/mL) | 23.18 ± 2.57 a | 95.88 ± 10.00a | 62.85 ± 9.35ab | 46.98 ± 23.54ab | 42.17 ± 7.33abcd | 40.67 ± 7.51abcd | 65.718 | < 0.001 |
| TGF-β (pg/mL) | 54.52 ± 6.91 a | 121.62 ± 5.07a | 69.03 ± 6.41ab | 67.27 ± 6.58ab | 53.52 ± 4.96bcd | 72.93 ± 9.02abe | 85.546 | < 0.001 |
| Endothlin-1 (ng/mL) | 4.18 ± 0.48 a | 16.07 ± 2.89a | 9.27 ± 1.06ab | 6.18 ± 1.01bc | 4.93 ± 0.48bc | 4.82 ± 0.75bc | 64.234 | < 0.001 |
The results are presented as the means ± standard deviation (SD). The groups with different superscripts in the same row are significantly different (p < 0.05), a: control group; b: model (dexamethasone-treated) group; c: PRV 0.5 mg/kg group; d: PRV1mg/kg group; e: PRV 2 mg/kg group.
n number/group, PRV propolis, royal jelly & bee venom, TGF-β transforming growth factor beta.