Table 1.
Characteristics of patients with type 2 diabetes.
| Variables | Group A (without AE, n=27) | Group B (with AE, n=23) | P value |
|---|---|---|---|
| Age (years) | 68.20 ± 7.03 | 68.74 ± 5.77 | 0.436a |
| Height (cm) | 167.50 ± 8.22 | 161.61 ± 8.94 | 0.019a |
| Male/female | 18/9 | 9/14 | 0.087b |
| Body mass index (kg/m2) | 24.79 ± 2.89 | 25.82 ± 2.88 | 0.217 a |
| Systolic BP (mmHg) | 134.00 ± 10.83 | 133.78 ± 16.01 | 0.470 a |
| Diastolic BP (mmHg) | 74.82 ± 6.72 | 77.70 ± 8.58 | 0.189 a |
| FBG (mmol/L; before T) | 7.96 ± 1.91 | 8.20 ± 1.93 | 0.225 a |
| FBG (mmol/L; post T) | 7.52 ± 1.46 | 7.71 ± 1.71 | 0.267 a |
| Fasting insulin (mIU/L) | 9.02 ± 4.67 | 8.89 ± 4.54 | 0.932 a |
| HOMA-IR (before T) | 3.23 ± 1.89 | 3.22 ± 2.01 | 0.798a |
| HbA1c (%; before T) | 8.09 ± 0.47 | 8.1 ± 0.5 | 0.934 a |
| HbA1c (%; post T) | 7.22 ± 0.62 | 7.16 ± 0.56 | 0.840 a |
| HbA1c reduction | 1.03 ± 0.29 | 0.93 ± 0.44 | 0.218 a |
| Acetic acid (mmol/L, before T) | 39.9 ± 4.3 | 38.0 ± 5.1 | 0.552 a |
| Propanoic (mmol/L, before T) | 2.6 ± 0.7 | 2.4 ± 0.8 | 0.347 a |
| Butyric (mmol/L, before T) | 1.5 ± 0.5 | 1.7 ± 0.4 | 0.377 a |
| Acetic acid (mmol/L, post T) | 45.6 ± 7.3 | 44.2 ± 8.1 | 0.533 a |
| Propanoic (mmol/L, post T) | 3.0 ± 0.8 | 3.5 ± 0.7 | 0.022 a |
| Butyric (mmol/L, post T) | 1.6 ± 0.5 | 1.9 ± 0.7 | 0.265 a |
a and b, statistical analysis by t-test and χ2 test, respectively.
Normally distributed data were expressed as mean ± standard deviation.
AE, adverse events; FBG, fasting blood glucose; T, treatment;
HbA1c, hemoglobin Alc; HOMA-IR, homeostasis model assessment of insulin resistance.