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The change in percentage anti-citrullinated protein antibody (ACPA) glycosylation (A) and anti-CCP2 titre (B) at day 8, 15, 29, and 57 relative to day 1, plotted for individuals across placebo and 0.3 mL and 3 mL (n = 10) dose groups. Anti-CCP2 was measured by ELISA and Fab glycosylation by HPLC. Each box represents the range (min-max), including all data points.
