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. 2022 Oct 24;7(20):e144925. doi: 10.1172/jci.insight.144925

Figure 3. Single-cell sequencing showing change in genes regulated by TGF-β signaling.

Figure 3

(A) Overview of tissue to obtain results from scRNA-Seq. (B) Uniform manifold approximation and projection (UMAP) plot with all time points clustered and legend to the right of the plot. The MPC and macrophage (Mac) clusters are circled. Endo, endothelial; SMC/peri, smooth muscle cell/pericyte; Granulo, granulocyte. (C) Violin plots of genes marking MPCs and Macs. (D) Genes regulated by TGF-β in Macs from day 0 (uninjured), day 7, and day 21. (E) Genes regulated by TGF-β in MPCs from day 0 (uninjured), day 7, and day 21.